-non-canonical nucleic acid secondary structures in human biology and diseases (infective agents, cancer, neurodegenerative diseases)
LAB NEWS
- Positions for undergraduate students willing to perform experimental thesis starting in September 2025 are available
- Applications from prospective postgraduate students and highly motivated researchers are welcome at any time and can be submitted by email.
- Applications from prospective postdoctoral fellow are welcome.
WELL DONEMAURI, IRENE AND MANU'!
For the first application of CUT&Tag in Mycobacterium tuberculosis which revealed many surprises! Published in Nature Comm.
SUPER WORK BEATRICE!
For the publication in Nucleic Acids Research on the drug in clinical trials QN-302 which we show is active against liposrcoma through biding to G4s in the MDM2 promoter
WE'VE MADE BREAKTHROUGH ARTICLE IN NUCLEIC ACIDS RESEARCH!
CONGRATS IRENE AND MANU'!!!!
We show that i-Motifs do exist in live cells, mainly at gene promoters and are associated with increased transcription levels. Check out our latest CUT&Tag data